Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | SCN4A | P35499 | 2/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29975006 | 1.00 | DYRK1A (0.67) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL9776980 | 0.86 | DYRK1A (0.70) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL2116986 | 0.84 | NPC1 (0.68) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL19850784 | 0.83 | DYRK1A (0.67) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL8430889 | 0.83 | DYRK1A (0.70) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL9776965 | 0.82 | DYRK1A (0.65) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL16884504 | 0.82 | DYRK1A (0.65) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL23104940 | 0.80 | DYRK1A (1.00) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL23720640 | 0.80 | DYRK1A (0.62) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL211725 | 0.80 | DYRK1A (0.65) | DYRK1ANPC1RAB9ASMN1; SMN2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151536-A | Antiviral compounds, compositions and methods of use | 不列颠哥伦比亚大学 | 2022-10-04 | — | — | CN | disclosed |