Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | SCN4A | P35499 | 2/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834217 | 0.87 | DYRK1A (0.60) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A | |
| SCHEMBL6250112 | 0.86 | DYRK1A (0.61) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A | |
| SCHEMBL6254947 | 0.85 | DYRK1A (0.60) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A | |
| Hydrochloric Acid SCHEMBL6834656 | 0.85 | DYRK1A (0.60) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A | |
| SCHEMBL9776980 | 0.85 | DYRK1A (0.70) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A | |
| Hydrochloric Acid SCHEMBL6253890 | 0.84 | DYRK1A (0.59) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A | |
| SCHEMBL22436025 | 0.83 | DYRK1A (0.61) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A | |
| SCHEMBL2759560 | 0.83 | RAB9A (0.65) | DYRK1ARAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL2116986 | 0.83 | NPC1 (0.68) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A | |
| SCHEMBL19850784 | 0.82 | DYRK1A (0.67) | DYRK1ARAB9ANPC1SMN1; SMN2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107007598-A | 2‑（N ethyls）6 trifluoromethoxy benzo thiazoles as cancer therapy drug application | 西北工业大学 | 2017-08-04 | — | — | CN | claimed |
| CN-107007598-B | 2- (N- ethyl) -6- trifluoromethoxy benzo thiazole is preparing the application in anticancer drug | 西北工业大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-107007598-A | 2‑（N ethyls）6 trifluoromethoxy benzo thiazoles as cancer therapy drug application | 西北工业大学 | 2017-08-04 | — | — | CN | disclosed |
| US-5068238-A | Anticonvulsants, schizophrenia, sleep disorders, antiischemia agents and cognition activators | RHONE-POULENC SANTE (FR) | 1991-11-26 | — | — | US | disclosed |