Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | CDK9 | P50750 | 1/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401175 | 0.86 | SMN1; SMN2 (0.80) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| SCHEMBL28051724 | 0.83 | TAS2R38 (0.63) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| SCHEMBL19501793 | 0.83 | NPC1 (1.00) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| SCHEMBL8428905 | 0.82 | SMN1; SMN2 (0.73) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| SCHEMBL21511125 | 0.82 | SMN1; SMN2 (0.59) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| Acetanilide SCHEMBL24681 | 0.81 | NAPRT (1.00) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| SCHEMBL19669626 | 0.81 | NAPRT (1.00) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| Acetanilide SCHEMBL1332076 | 0.81 | NAPRT (1.00) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| Acetanilide SCHEMBL3359084 | 0.81 | NAPRT (1.00) | NPC1RAB9AKMT2ATAAR1NAPRT | |
| Acetanilide SCHEMBL16922180 | 0.81 | NAPRT (1.00) | NPC1RAB9AKMT2ATAAR1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11781029-B2 | Heat-sensitive recording material | PAPIERFABRIK AUGUST KOEHLER SE (DE) | 2023-10-10 | — | — | US | disclosed |
| CN-109563041-B | 1-acetyl-3-phenylurea compounds and uses thereof | 住友化学株式会社 | 2021-12-07 | — | — | CN | disclosed |
| CN-109563041-B | 1-acetyl-3-phenylurea compounds and uses thereof | 住友化学株式会社 | 2021-12-07 | — | — | CN | disclosed |
| US-10893676-B2 | 1-acetyl-3-phenyl urea compound, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-01-19 | — | — | US | disclosed |
| US-10893676-B2 | 1-acetyl-3-phenyl urea compound, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-01-19 | — | — | US | disclosed |
| US-20190174762-A1 | 1-ACETYL-3-PHENYL UREA COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-06-13 | — | — | US | disclosed |
| CN-108349968-A | antibacterial therapeutic and prophylactic agents | 维奥梅生物科学私人有限公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2010149786-A1 | PYRIDO [2, 3-D] PYRIMIDINES AS WNT ANTAGONISTS FOR TREATMENT OF CANCER AND ARTHRITIS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2010-12-29 | — | — | WO | disclosed |
| EP-2266984-A1 | Pyrido[2,3-d]pyrimidines as Wnt antagonists for treatment of cancer and arthritis | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2010-12-29 | — | — | EP | disclosed |
| US-7666977-B2 | Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-02-23 | — | — | US | disclosed |
| US-7557175-B2 | Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-07-07 | — | — | US | disclosed |
| US-7511110-B2 | Crosslinkable polyorganosiloxane compositions | WACKER CHEMIE AG (DE) | 2009-03-31 | — | — | US | disclosed |
| WO-2008136842-A1 | POLY( CARBONATE-CO-UREA) COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008136841-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-11-13 | — | — | WO | disclosed |
| US-20080275209-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | GENERAL ELECTRIC COMPANY (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080275206-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | GENERAL ELECTRIC COMPANY (US) | 2008-11-06 | — | — | US | disclosed |
| US-20060135689-A1 | Crosslinkable polyorganosiloxane compositions | WACKER CHEMIE GMBH (DE) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10893676-B2 | 1-acetyl-3-phenyl urea compound, and use thereof | NAT1, SAT1, CPS1 | NPC1 1553/4885RAB9A 3035/4885KMT2A 2347/4885 |
| US-20190174762-A1 | 1-ACETYL-3-PHENYL UREA COMPOUND, AND USE THEREOF | NAT1, SAT1, CPS1 | NPC1 1553/4885RAB9A 3035/4885KMT2A 2347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.