⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29970803 | 0.80 | POLB (0.35) | — | |
| SCHEMBL23273954 | 0.80 | POLB (0.35) | — | |
| SCHEMBL12506002 | 0.74 | ADK (0.31) | — | |
| SCHEMBL30402638 | 0.74 | ADK (0.31) | — | |
| SCHEMBL15067054 | 0.71 | SRC (0.44) | — | |
| SCHEMBL9972993 | 0.70 | ADORA2A (0.33) | — | |
| SCHEMBL30053919 | 0.64 | SRC (0.36) | — | |
| SCHEMBL23834493 | 0.64 | SRC (0.36) | — | |
| SCHEMBL30373137 | 0.64 | PI4KA (0.41) | — | |
| SCHEMBL29546343 | 0.61 | CSNK2A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279756-A | METTL3 modulators | 埃克森特治疗公司 | 2022-11-01 | — | — | CN | disclosed |