Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445164 | 0.91 | — | — | |
| SCHEMBL6047854 | 0.89 | TSHR (0.35) | TSHRESR1ESR2KDM4ENPC1 | |
| SCHEMBL103755 | 0.88 | ESR1 (0.37) | TSHRESR1ESR2KDM4ENPC1 | |
| SCHEMBL16774534 | 0.87 | TSHR (0.34) | TSHRESR1ESR2KDM4ENPC1 | |
| SCHEMBL854785 | 0.86 | TSHR (0.36) | TSHRESR1ESR2KDM4ENPC1 | |
| SCHEMBL6046631 | 0.86 | TSHR (0.33) | TSHRTP53 | |
| SCHEMBL28188516 | 0.85 | ESR1 (0.32) | TSHRESR1ESR2TP53 | |
| SCHEMBL3301397 | 0.84 | TSHR (0.33) | TSHRESR1ESR2KDM4ENPC1 | |
| SCHEMBL27323401 | 0.83 | TSHR (0.31) | TSHR | |
| SCHEMBL4361107 | 0.82 | ESR1 (0.33) | TSHRESR1ESR2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286924-A | Silicone rubber self-bleeding oil auxiliary agent master batch, self-bleeding oil silicone rubber and preparation method | 浙江新安化工集团股份有限公司 | 2022-11-04 | — | — | CN | disclosed |