Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103755 | 0.94 | ESR1 (0.37) | ESR1ESR2KDM4EALDH1A1TP53 | |
| SCHEMBL6047854 | 0.86 | TSHR (0.35) | ESR1ESR2KDM4EALDH1A1TP53 | |
| SCHEMBL3294085 | 0.84 | LMNA (0.35) | ESR1ESR2KDM4EALDH1A1TP53 | |
| SCHEMBL16207633 | 0.83 | ESR1 (0.33) | ESR1ESR2KDM4EALDH1A1TP53 | |
| SCHEMBL10609485 | 0.83 | ESR1 (0.33) | ESR1ESR2KDM4EALDH1A1TP53 | |
| SCHEMBL854785 | 0.83 | TSHR (0.36) | ESR1ESR2KDM4EALDH1A1TP53 | |
| SCHEMBL28879207 | 0.82 | TSHR (0.33) | ESR1ESR2KDM4EALDH1A1TP53 | |
| SCHEMBL707974 | 0.82 | NQO1 (0.33) | ESR1ESR2 | |
| SCHEMBL8853348 | 0.82 | ESR1 (0.36) | ESR1ESR2KDM4EALDH1A1TP53 | |
| SCHEMBL6670319 | 0.82 | ESR1 (0.32) | ESR1ESR2KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2138501-B1 | Functional silane compound, coating solution, and method for manufacturing plastic lens | HOYA CORP (JP) | 2014-08-13 | — | — | EP | disclosed |
| EP-2138501-A2 | Functional silane compound, coating solution, and method for manufacturing plastic lens | Hoya Corporation (JP) | 2009-12-30 | — | — | EP | disclosed |