SCHEMBL28879338

SCHEMBL28879338

COc1cc(OC)c2c(c1OC)OC(c1ccccc1)CC2=O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 0.77
ABCB1 P08183 3/20 0.77
MEN1 O00255 1/20 0.76
POLB P06746 1/20 0.76
GAA P10253 1/20 0.76
MAPT P10636 1/20 0.76
PABPC1 P11940 1/20 0.76
APEX1 P27695 1/20 0.76
RECQL P46063 1/20 0.76
KMT2A Q03164 1/20 0.76
EIF4H Q15056 1/20 0.76
L3MBTL1 Q9Y468 1/20 0.76
CYP19A1 P11511 2/20 0.63
KDM4E B2RXH2 2/20 0.62
ALDH1A1 P00352 2/20 0.62
HPGD P15428 2/20 0.62
HSD17B10 Q99714 2/20 0.62
CYP3A4 P08684 1/20 0.62
MAPK1 P28482 1/20 0.62
NPC1 O15118 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045887 0.90 CYP19A1 (0.78) ABCG2ABCB1MEN1POLBGAA
SCHEMBL28513250 0.89 MEN1 (0.74) ABCG2ABCB1MEN1POLBGAA
SCHEMBL16894644 0.86 ABCG2 (0.58) ABCG2ABCB1MEN1POLBGAA
SCHEMBL30912310 0.86 ABCG2 (0.58) ABCG2ABCB1MEN1POLBGAA
SCHEMBL28336829 0.84 MEN1 (0.58) ABCG2ABCB1MEN1POLBGAA
SCHEMBL31238137 0.84 ABCG2 (0.72) ABCG2ABCB1MEN1POLBGAA
SCHEMBL28110754 0.84 ABCG2 (0.61) ABCG2ABCB1MEN1POLBGAA
SCHEMBL10425232 0.83 ABCG2 (0.60) ABCG2ABCB1MEN1POLBGAA
SCHEMBL10425231 0.82 ABCG2 (0.70) ABCG2ABCB1MEN1POLBGAA
SCHEMBL9063227 0.82 CYP19A1 (0.70) ABCG2ABCB1MEN1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110604774-A Traditional Chinese medicine composition for treating animal enteritis diarrhea and preparation method thereof 临沂金翠兽药有限公司 2019-12-24 CN disclosed
CN-110604762-A Traditional Chinese medicine composition for treating kidney-type infectious bronchitis of poultry and preparation method thereof 临沂金翠兽药有限公司 2019-12-24 CN disclosed