Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907269 | 0.90 | MEN1 (0.67) | ABCG2ABCB1MAPTMEN1POLB | |
| SCHEMBL16894664 | 0.90 | MAOB (0.60) | ABCG2ABCB1MAPTCYP19A1MAOB | |
| SCHEMBL16894614 | 0.89 | PTAFR (0.49) | ABCG2ABCB1MAPTMEN1POLB | |
| SCHEMBL30674790 | 0.89 | MAOB (0.57) | ABCG2ABCB1MAPTMEN1POLB | |
| SCHEMBL16894660 | 0.87 | ODC1 (0.50) | ABCG2ABCB1MAPTMEN1POLB | |
| SCHEMBL19736057 | 0.84 | CYP19A1 (0.62) | ABCG2MAPTMEN1POLBGAA | |
| SCHEMBL28879338 | 0.83 | ABCG2 (0.77) | ABCG2ABCB1MAPTMEN1POLB | |
| SCHEMBL16894629 | 0.83 | CYP19A1 (0.52) | ABCG2ABCB1MAPTMEN1POLB | |
| SCHEMBL4050327 | 0.83 | ABCG2 (0.50) | ABCG2ABCB1MAPTMEN1POLB | |
| SCHEMBL2879029 | 0.82 | ABCG2 (0.67) | ABCG2ABCB1MAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935441-A | Flavene and thioflavene derivates, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | ZYMA SA (CH) | 1990-06-19 | — | — | US | disclosed |
| EP-0139615-B1 | FLAVENE AND THIOFLAVENE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SUCH COMPOUNDS, AND THE USE OF THE LATTER | Zyma SA (CH) | 1989-04-19 | — | — | EP | disclosed |
| EP-0139615-A2 | Flavene and thioflavene derivatives, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | Zyma SA (CH) | 1985-05-02 | — | — | EP | disclosed |