Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401848 | 0.75 | LMNA (0.46) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL31095029 | 0.75 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL23727589 | 0.75 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL20495315 | 0.75 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL6542235 | 0.75 | TSHR (0.63) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL10820771 | 0.74 | TSHR (0.92) | TSHRLMNANFKB1PMP22GPR84 | |
| Water SCHEMBL28578358 | 0.74 | TSHR (0.92) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL3832481 | 0.74 | TSHR (0.92) | TSHRLMNANFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL20235882 | 0.74 | TSHR (0.92) | TSHRLMNANFKB1PMP22GPR84 | |
| Azelaic Acid SCHEMBL9806002 | 0.74 | TSHR (0.92) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110577940-B | Kluyveromyces marxianus aldehyde ketone reductase KmAKR mutant and application thereof | 浙江工业大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-110004120-B | Recombinant aldone reductase mutant and application thereof | 浙江工业大学 | 2021-02-02 | — | — | CN | disclosed |
| CN-110577940-A | Kluyveromyces marxianus aldehyde ketone reductase KmAKR mutant and application thereof | 浙江工业大学 | 2019-12-17 | — | — | CN | disclosed |