Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434009 | 1.00 | ADRB2 (0.40) | ADRB2ADORA3ADRB1ELANEPIK3CG | |
| SCHEMBL18016231 | 0.87 | ADRB2 (0.39) | ADRB2ADORA3ADRB1ELANEPIK3CG | |
| SCHEMBL776314 | 0.86 | ADRB2 (0.39) | ADRB2ADORA3ADRB1ELANEPIK3CG | |
| SCHEMBL14617522 | 0.86 | ADRB2 (0.39) | ADRB2ADORA3ADRB1ELANEPIK3CG | |
| SCHEMBL384325 | 0.86 | ADRB2 (0.39) | ADRB2ADORA3ADRB1ELANEPIK3CG | |
| SCHEMBL3586934 | 0.86 | ADRB2 (0.39) | ADRB2ADORA3ADRB1ELANEPIK3CG | |
| SCHEMBL1310653 | 0.84 | ADRB2 (0.40) | ADRB2ADORA3ADRB1DRD2DRD1 | |
| SCHEMBL1310655 | 0.84 | ADRB2 (0.40) | ADRB2ADORA3ADRB1DRD2DRD1 | |
| SCHEMBL28446409 | 0.83 | ADRB2 (0.38) | ADRB2ADORA3ADRB1ELANEDRD2 | |
| SCHEMBL385179 | 0.83 | ADRB2 (0.39) | ADRB2ADORA3ADRB1DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107690432-B | Compounds having muscarinic receptor antagonist and beta 2 adrenergic receptor agonist activity | 奇斯药制品公司 | 2019-12-24 | — | — | CN | disclosed |