Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248688 | 0.81 | GAA (0.40) | MAPTGAA | |
| SCHEMBL6010290 | 0.75 | GAA (0.52) | MAPTGAACYP1A2NPC1SMN1; SMN2 | |
| SCHEMBL28401077 | 0.75 | GAA (0.40) | MAPTGAA | |
| SCHEMBL3732226 | 0.74 | GAA (0.50) | MAPTGAALMNASMN1; SMN2 | |
| SCHEMBL9286080 | 0.74 | KMT2A (0.41) | MAPTGAAKDM4E | |
| SCHEMBL15630460 | 0.70 | MAPT (0.50) | MAPTGAAKDM4ELMNACCR1 | |
| SCHEMBL28744109 | 0.69 | GAA (0.44) | MAPTGAA | |
| SCHEMBL11774509 | 0.69 | KDM4E (0.42) | MAPTGAAKDM4ELMNACCR1 | |
| SCHEMBL5094762 | 0.67 | MAPT (0.61) | MAPTGAACYP1A2POLBRAB9A | |
| SCHEMBL7414784 | 0.66 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135628-A | Compounds for fast and efficient click release | 泰克沃尔科斯制药有限公司 | 2022-09-30 | — | — | CN | disclosed |