Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31188758 | 1.00 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL29605097 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL30823596 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL30462264 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL9935617 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL31482354 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL8769697 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL29181630 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL460837 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL6312855 | 0.75 | MAPT (0.54) | MAPTGAARAB9ASMN1; SMN2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059958-A | Method for aryl debromination acylation of bromobenzazepine compounds | 上海沃凯生物技术有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-119059958-A | Method for aryl debromination acylation of bromobenzazepine compounds | 上海沃凯生物技术有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-119059958-A | Method for aryl debromination acylation of bromobenzazepine compounds | 上海沃凯生物技术有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-119059958-A | Method for aryl debromination acylation of bromobenzazepine compounds | 上海沃凯生物技术有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-115286566-B | Synthesis method of pheniramine or derivatives thereof | 南京农业大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-116368168-A | Novel antimicrobial and antithrombotic medical device | 列日大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-106164044-B | Process for producing 1-arylimino-2-vinylcyclopropanecarboxylic acid derivative | 株式会社钟化 | 2018-05-04 | — | — | CN | disclosed |
| CN-106164044-A | Process for producing 1-arylimino-2-vinylcyclopropanecarboxylic acid derivative | 株式会社钟化 | 2016-11-23 | — | — | CN | disclosed |
| CN-1859949-A | New derivative of 4A,5,9,10,11,12-tetrahydro-6H-benzofuro[3A, 3, 2-EF] [2] benzazepinium bromide, method of preparation thereof and use in the production of medicaments | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2006-11-08 | — | — | CN | disclosed |
| US-5063230-A | Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-11-05 | — | — | US | disclosed |
| WO-1990006113-A1 | SUBSTITUTED SATURATED AND UNSATURATED INDOLE QUINOLINE AND BENZAZEPINE CARBOXAMIDES AND THEIR USE AS PHARMACOLOGICAL AGENTS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1990-06-14 | — | — | WO | disclosed |
| EP-0230755-B1 | 1-PHENYL-3-BENZAZEPINES | SMITHKLINE BEECHAM CORPORATION (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4920219-A | Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4707483-A | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders | SMITHKLINE BECKMAN CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0230755-A1 | 1-Phenyl-3-benzazepines | SMITHKLINE BEECHAM CORPORATION (US) | 1987-08-05 | — | — | EP | disclosed |