Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30717 | 0.71 | LPL (0.40) | LPLLIPGP2RX7CA1CA2 | |
| SCHEMBL17827632 | 0.68 | PRKCI (0.37) | LPLLIPGMAPK1 | |
| SCHEMBL18239777 | 0.68 | PRKCI (0.37) | LPLLIPG | |
| SCHEMBL18239899 | 0.68 | IRAK4 (0.36) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL31378574 | 0.68 | JAK2 (0.43) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL1529678 | 0.68 | FFAR1 (0.36) | LPLLIPGP2RX7 | |
| SCHEMBL18103626 | 0.67 | LPL (0.44) | LPLLIPGP2RX7CA1CA2 | |
| SCHEMBL2573893 | 0.66 | LPL (0.40) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL18092423 | 0.66 | JAK2 (0.41) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL19885232 | 0.64 | LPL (0.41) | LPLLIPGP2RX7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-B | Morpholine derivative, and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022152229-A1 | CLASS OF MORPHOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-07-21 | — | — | WO | disclosed |