Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620524 | 0.88 | HCRTR1 (0.41) | HCRTR1HCRTR2KMT2AKDM4ECYP2C9 | |
| SCHEMBL27620525 | 0.88 | HCRTR1 (0.41) | HCRTR1HCRTR2KMT2AKDM4ECYP2C9 | |
| SCHEMBL6575508 | 0.87 | CKS1B (0.41) | HCRTR1HCRTR2KMT2AKDM4EEPHX2 | |
| SCHEMBL1598078 | 0.87 | CKS1B (0.41) | HCRTR1HCRTR2KMT2AKDM4EEPHX2 | |
| SCHEMBL6575510 | 0.87 | CKS1B (0.41) | HCRTR1HCRTR2KMT2AKDM4EEPHX2 | |
| SCHEMBL6222489 | 0.84 | HCRTR1 (0.61) | HCRTR1HCRTR2CCR3TP53CYP2D6 | |
| SCHEMBL6221269 | 0.84 | HCRTR1 (0.61) | HCRTR1HCRTR2CCR3TP53CYP2D6 | |
| SCHEMBL6221273 | 0.84 | HCRTR1 (0.61) | HCRTR1HCRTR2CCR3TP53CYP2D6 | |
| SCHEMBL6221470 | 0.84 | CKS1B (0.43) | HCRTR1HCRTR2KMT2AKDM4E | |
| SCHEMBL6221463 | 0.84 | CKS1B (0.43) | HCRTR1HCRTR2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286201-A1 | POLYMORPH FORMS OF (S)-2-((4-BENZOFURANYL)CARBONYLAMINOMETHYL)-1-((4-(2-METHYL-5-(4-FLUOROPHENYL)THIAZOLYL)CARBONYL)PIPERIDINE | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286201-A1 | POLYMORPH FORMS OF (S)-2-((4-BENZOFURANYL)CARBONYLAMINOMETHYL)-1-((4-(2-METHYL-5-(4-FLUOROPHENYL)THIAZOLYL)CARBONYL)PIPERIDINE | HLA-DRB1, HLA-C, BRCA1 | HCRTR1 4137/4885HCRTR2 3700/4885KMT2A 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.