Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 9/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888023 | 0.96 | CXCR4 (0.53) | SMN1; SMN2CXCR4CHRM5CHRM3MEN1 | |
| SCHEMBL4904768 | 0.94 | SMN1; SMN2 (0.49) | SMN1; SMN2CXCR4CHRM5CHRM3MEN1 | |
| SCHEMBL154268 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL13833167 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL1974799 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL1393824 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL10667505 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2CHRM5CHRM3MEN1KMT2A | |
| SCHEMBL3422751 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2CXCR4CHRM5CHRM3MEN1 | |
| SCHEMBL20565492 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2CHRM5CHRM3MAPTRAD52 | |
| SCHEMBL22014102 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2CHRM5CHRM3MAPTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153934-B | Polyester dispersants, synthesis and uses thereof | 雪佛龙奥伦耐有限责任公司 | 2022-04-05 | — | — | CN | claimed |
| US-20240293364-A1 | BIOMARKERS FOR CANCER THERAPY USING MDM2 ANTAGONISTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-09-05 | — | — | US | disclosed |
| US-20230338337-A1 | BIOMARKERS FOR CANCER THERAPY USING MDM2 ANTAGONISTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230313313-A1 | BIOMARKERS FOR CANCER THERAPY USING MDM2 ANTAGONISTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-10-05 | — | — | US | disclosed |
| CN-109153934-B | Polyester dispersants, synthesis and uses thereof | 雪佛龙奥伦耐有限责任公司 | 2022-04-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293364-A1 | BIOMARKERS FOR CANCER THERAPY USING MDM2 ANTAGONISTS | MSH2, MRE11, RAD50 | SMN1; SMN2 3064/4885CXCR4 2124/4885CHRM5 4788/4885 |
| US-20230313313-A1 | BIOMARKERS FOR CANCER THERAPY USING MDM2 ANTAGONISTS | SKP2, MDM2, TP53 | SMN1; SMN2 3472/4885CXCR4 2814/4885CHRM5 4849/4885 |
| US-20230338337-A1 | BIOMARKERS FOR CANCER THERAPY USING MDM2 ANTAGONISTS | IRF2BP2, BST2, IRF3 | SMN1; SMN2 3980/4885CXCR4 1408/4885CHRM5 4729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.