SCHEMBL3422751

SCHEMBL3422751

CC(O)CN1CCNCCNCCNCC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.55
CHRM5 P08912 1/20 0.44
CHRM3 P20309 1/20 0.44
RAD52 P43351 1/20 0.40
IDO1 P14902 1/20 0.39
CXCR4 P61073 2/20 0.38
BAX Q07812 1/20 0.37
DRD2 P14416 2/20 0.37
DRD3 P35462 2/20 0.37
POLB P06746 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
BRD4 O60885 1/20 0.35
PADI1 Q9ULC6 1/20 0.35
PADI4 Q9UM07 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperazine SCHEMBL28217692 1.00 SMN1; SMN2 (0.55) SMN1; SMN2CHRM5CHRM3RAD52IDO1
Hydrochloric Acid SCHEMBL21178220 0.98 SMN1; SMN2 (0.58) SMN1; SMN2CHRM5CHRM3RAD52IDO1
Hydrochloric Acid SCHEMBL8296060 0.98 SMN1; SMN2 (0.58) SMN1; SMN2CHRM5CHRM3RAD52IDO1
SCHEMBL13833167 0.98 SMN1; SMN2 (0.56) SMN1; SMN2CHRM5CHRM3RAD52IDO1
SCHEMBL1974799 0.98 SMN1; SMN2 (0.56) SMN1; SMN2CHRM5CHRM3RAD52IDO1
SCHEMBL1393824 0.98 SMN1; SMN2 (0.56) SMN1; SMN2CHRM5CHRM3RAD52IDO1
SCHEMBL154268 0.98 SMN1; SMN2 (0.56) SMN1; SMN2CHRM5CHRM3RAD52IDO1
SCHEMBL10667505 0.98 SMN1; SMN2 (0.56) SMN1; SMN2CHRM5CHRM3RAD52IDO1
SCHEMBL22014102 0.95 SMN1; SMN2 (0.55) SMN1; SMN2CHRM5CHRM3RAD52IDO1
SCHEMBL20565492 0.95 SMN1; SMN2 (0.55) SMN1; SMN2CHRM5CHRM3RAD52IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019143073-A1 GADOTERIDOL INTERMEDIATE AND METHOD FOR PREPARING GADOTERIDOL USING SAME 주식회사 엔지켐생명과학 2019-07-25 WO claimed
WO-2024085723-A1 FERRITIN PROTEIN STRUCTURE DISPLAYING SARS-COV-2 S1-DERIVED PROTEIN AND ANTIBODY FC REGION PROTEIN SIMULTANEOUSLY ON SURFACE, AND USE THEREOF FOR VACCINE FOR CORONAVIRUS SARS-COV-2 충남대학교 산학협력단 2024-04-25 WO disclosed
US-11905257-B2 Manufacturing process for preparing gadoteridol BRACCO IMAGING S.P.A. (IT) 2024-02-20 US disclosed
WO-2023245169-A1 ANTIMICROBIAL PEPTIDE COMBINATIONS Vestaron Corporation (US) 2023-12-21 WO disclosed
WO-2023245100-A1 ANTIMICROBIAL NCR13 VARIANT PEPTIDES Vestaron Corporation (US) 2023-12-21 WO disclosed
US-20230391735-A1 MANUFACTURING PROCESS FOR PREPARING GADOTERIDOL BRACCO IMAGING S.P.A. (IT) 2023-12-07 US disclosed
CN-114085192-B Refining method of gadoteridol intermediate 海南普利制药股份有限公司 2023-09-19 CN disclosed
CN-116209679-A Antibody-drug conjugates containing anti-mesothelin antibodies and uses thereof 财团法人生物技术开发中心 2023-06-02 CN disclosed
CN-114105897-B Preparation method of gadoteridol 安徽普利药业有限公司 2023-04-04 CN disclosed
CN-109952375-B Novel anti-human MUC1 antibody Fab fragment 安斯泰来制药株式会社 2022-11-18 CN disclosed
WO-2019143073-A1 GADOTERIDOL INTERMEDIATE AND METHOD FOR PREPARING GADOTERIDOL USING SAME 주식회사 엔지켐생명과학 2019-07-25 WO disclosed
WO-2018138280-A1 NANOMATERIAL AND METHOD OF PRODUCTION OF A NANOMATERIAL FOR MEDICAL APPLICATIONS, SUCH AS MRI OR SERS UNIVERSITE PARIS NORD (FR) 2018-08-02 WO disclosed
EP-2766364-A1 FOLATE CONJUGATES OF ALBUMIN-BINDING ENTITIES Merck & Cie (CH) 2014-08-20 EP disclosed
WO-2013024035-A1 FOLATE CONJUGATES OF ALBUMIN-BINDING ENTITIES Merck & Cie (CH) 2013-02-21 WO disclosed
EP-2170406-A2 A METHOD OF HYPERPOLARISING A MAGNETIC RESONANCE AGENT Gadian, David (GB) 2010-04-07 EP disclosed
WO-2009004357-A2 A METHOD OF HYPERPOLARISING A MAGNETIC RESONANCE AGENT UNIVERSITY COLLEGE LONDON (GB) 2009-01-08 WO disclosed
EP-0545511-B1 Process for the preparation of mono-N-substituted tetraazamacrocycles SCHERING AG (DE) 2002-05-29 EP disclosed
US-6380169-B1 FOR INHIBITING MESSENGER RNA TRANSLATION USING ANTI-SENSE OLIGONUCLEOSIDES CONTAINING 5'-CAP CLEAVAGE MOIETIES ISIS PHARMACEUTICALS, INC. 2002-04-30 US disclosed
US-5410043-A Chemical intermediate for metal complexes SCHERING AKTIENGESELLSCHAFT (DE) 1995-04-25 US disclosed
EP-0545511-A2 Process for the preparation of mono-N-substituted tetraazamacrocycles SCHERING AKTIENGESELLSCHAFT (DE) 1993-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391735-A1 MANUFACTURING PROCESS FOR PREPARING GADOTERIDOL SSTR2, GCG, ADCYAP1R1 SMN1; SMN2 3067/4885CHRM5 1504/4885CHRM3 628/4885
US-11905257-B2 Manufacturing process for preparing gadoteridol SSTR2, GCG, ADCYAP1R1 SMN1; SMN2 3067/4885CHRM5 1504/4885CHRM3 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.