Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287072 | 0.81 | KDM4C (0.55) | MAPTMAPK1ALDH1A1KDM4ENPC1 | |
| SCHEMBL30378291 | 0.81 | KDM4C (0.55) | MAPTMAPK1ALDH1A1KDM4ENPC1 | |
| SCHEMBL29072870 | 0.79 | KMT2A (0.43) | MAPTMAPK1POLBALDH1A1KDM4E | |
| SCHEMBL28404952 | 0.79 | MAPT (0.44) | MAPTMAPK1POLBCYP1A2ALDH1A1 | |
| SCHEMBL15991431 | 0.78 | CYP1A2 (0.46) | MAPTPOLBCYP1A2ALDH1A1KDM4E | |
| SCHEMBL14825305 | 0.78 | JMJD6 (0.53) | CYP1A2LMNACYP3A4KDM5CKDM4C | |
| Nitrous Acid SCHEMBL28883192 | 0.78 | KDM4C (0.49) | MAPTALDH1A1KDM4EKDM5CKDM4C | |
| SCHEMBL28781584 | 0.77 | NPC1 (0.42) | MAPTMAPK1POLBALDH1A1KDM4E | |
| SCHEMBL30560163 | 0.76 | KDM4C (0.55) | MAPTALDH1A1KDM4EKDM5CKDM4C | |
| SCHEMBL28331934 | 0.76 | KDM4C (0.55) | MAPTALDH1A1KDM4EKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799509-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2020-02-14 | — | — | CN | disclosed |