Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.49 |
| ▸ | KDM5C | P41229 | 7/20 | 0.49 |
| ▸ | KDM4A | O75164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | KDM6B | O15054 | 4/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 4/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.49 |
| ▸ | KDM5A | P29375 | 2/20 | 0.49 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ASPH | Q12797 | 1/20 | 0.49 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.49 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.49 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.49 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.49 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30560163 | 0.93 | KDM4C (0.55) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL28331934 | 0.93 | KDM4C (0.55) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL28883191 | 0.78 | MAPT (0.39) | KDM4CKDM5CKDM4EKDM6BKDM2A | |
| Nitrous Acid SCHEMBL29072872 | 0.77 | KDM4C (0.53) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| Nitrous Acid SCHEMBL28404954 | 0.77 | KDM4C (0.53) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL15991431 | 0.77 | CYP1A2 (0.46) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL2305108 | 0.77 | KDM4C (0.57) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL7670706 | 0.77 | KDM4C (0.57) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL1647272 | 0.75 | CYP1A2 (0.61) | KDM4CKDM5CKDM4AKDM4EKDM6B | |
| SCHEMBL12252467 | 0.75 | GABRP (0.58) | KDM4CKDM5CKDM4AKDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799509-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2020-02-14 | — | — | CN | disclosed |