Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 6/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775106 | 0.84 | EPHX1 (0.41) | NOS2NOS3NOS1DPP4HTR2C | |
| SCHEMBL4336849 | 0.84 | EPHX1 (0.41) | NOS2NOS3NOS1DPP4HTR2C | |
| SCHEMBL2637808 | 0.82 | NOS2 (0.42) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL27795896 | 0.80 | EPHX1 (0.39) | NOS2NOS3NOS1EPHX1 | |
| SCHEMBL2494402 | 0.76 | NOS2 (0.43) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL27796013 | 0.75 | NOS2 (0.38) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL27795961 | 0.75 | NOS2 (0.38) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL27775234 | 0.72 | NOS2 (0.36) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL18394515 | 0.72 | NOS2 (0.39) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL16586213 | 0.69 | DPP4 (0.35) | NOS2NOS3NOS1DPP4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799218-A | Antibody conjugates comprising STING agonists | 诺华股份有限公司 | 2020-02-14 | — | — | CN | disclosed |