Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203727 | 0.92 | ADAM10 (0.48) | HTR2CNPC1RAB9ASMN1; SMN2ADAM10 | |
| SCHEMBL6120151 | 0.92 | ADAM10 (0.48) | HTR2CNPC1RAB9ASMN1; SMN2ADAM10 | |
| SCHEMBL16554922 | 0.88 | HTR2C (0.44) | HTR2CSMN1; SMN2ADAM10MMP2MMP3 | |
| SCHEMBL16554923 | 0.88 | HTR2C (0.44) | HTR2CSMN1; SMN2ADAM10MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL16555025 | 0.87 | HTR2C (0.43) | HTR2CADAM10MMP2MMP3MMP9 | |
| Hydrochloric Acid SCHEMBL16555026 | 0.87 | HTR2C (0.43) | HTR2CADAM10MMP2MMP3MMP9 | |
| SCHEMBL1440900 | 0.86 | MEN1 (0.50) | HTR2CNPC1RAB9ASMN1; SMN2ADAM10 | |
| Hydrochloric Acid SCHEMBL27225666 | 0.81 | HTR2C (0.44) | HTR2CNPC1RAB9ASMN1; SMN2ADAM10 | |
| SCHEMBL12559646 | 0.80 | NPC1 (0.49) | HTR2CNPC1RAB9ASMN1; SMN2PSEN1 | |
| SCHEMBL17377956 | 0.80 | NPC1 (0.49) | HTR2CNPC1RAB9ASMN1; SMN2PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440507-B | Compound as apoptosis protein inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |