SCHEMBL28886019

SCHEMBL28886019

C=COC(C)OCc1ccccc1C=C

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 2/20 0.30
ADRB2 P07550 3/20 0.30
ADRB1 P08588 3/20 0.30
LMNA P02545 1/20 0.30
HTR1A P08908 1/20 0.30
ADRB3 P13945 1/20 0.30
ADRA2C P18825 1/20 0.30
SLC6A2 P23975 1/20 0.30
BDKRB2 P30411 1/20 0.30
SLC6A4 P31645 1/20 0.30
ADRA1A P35348 1/20 0.30
HTR2B P41595 1/20 0.30
KCNH2 Q12809 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418590 0.90 ALDH1A1 (0.36) ALDH1A1TSHRADRB2ADRB1LMNA
SCHEMBL4895199 0.83 ALDH1A1 (0.36) ALDH1A1TSHRADRB2ADRB1LMNA
SCHEMBL28886017 0.83 ALDH1A1 (0.32) ALDH1A1
SCHEMBL8708901 0.81 ALDH1A1 (0.35) ALDH1A1TSHRADRB2ADRB1LMNA
SCHEMBL10628516 0.80 ALDH1A1 (0.34) ALDH1A1TSHRADRB2ADRB1LMNA
SCHEMBL28762268 0.79
SCHEMBL10623860 0.77 ALDH1A1 (0.32) ALDH1A1TSHRADRB2ADRB1LMNA
SCHEMBL2971587 0.76 TSHR (0.40) ALDH1A1TSHRLMNASLC6A2SLC6A4
SCHEMBL7871021 0.73 KDM4E (0.38) ALDH1A1TSHRADRB2ADRB1LMNA
SCHEMBL10624022 0.73 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057961-B Polymer double-chain/inorganic nanoparticle composite Janus material and preparation method thereof 清华大学 2022-11-18 CN claimed