SCHEMBL28889016

SCHEMBL28889016

CCC(C)OC(=O)C(CC)C(=O)OC(C)CC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
FAAH O00519 1/20 0.35
TSHR P16473 4/20 0.32
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM1 P11229 2/20 0.32
TBXA2R P21731 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 5/20 0.31
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31
CYP2C9 P11712 1/20 0.31
GALR3 O60755 1/20 0.31
BLM P54132 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15549609 0.91 MAPT (0.38) MAPTTSHRALDH1A1LMNASMN1; SMN2
SCHEMBL334795 0.91 MAPT (0.44) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL27561060 0.89 FAAH (0.40) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL27944130 0.87 FAAH (0.39) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL1706068 0.85 MAPT (0.41) MAPTFAAH
SCHEMBL28395655 0.84 FAAH (0.40) MAPTFAAHTSHRCHRM1LMNA
SCHEMBL779893 0.82 MAPT (0.43) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL6063173 0.82 TSHR (0.43) TSHRALDH1A1LMNAHSD17B10CA1
SCHEMBL2980611 0.82 MAPT (0.43) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL1216964 0.82 MAPT (0.43) MAPTFAAHTSHRCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032603-B Iron-catalyzed transesterification hydrogenation of esters to alcohols 伊士曼化工公司 2023-07-25 CN disclosed
CN-111032603-A Iron-catalyzed transfer hydrogenation of esters to alcohols 伊士曼化工公司 2020-04-17 CN disclosed