Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29942364 | 0.90 | ADRB2 (0.40) | KDM4ETDP1ALDH1A1MAPTADRB2 | |
| SCHEMBL29941818 | 0.89 | HDAC4 (0.41) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29941839 | 0.89 | PHGDH (0.41) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL29941697 | 0.89 | MEN1 (0.49) | TACR1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28889297 | 0.89 | ADRB2 (0.37) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29893817 | 0.89 | ADRB2 (0.37) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29942331 | 0.86 | ADRB2 (0.38) | KMT2AHTTKDM4EALDH1A1LMNA | |
| SCHEMBL29941794 | 0.86 | ADRB2 (0.38) | MEN1KMT2AHTTKDM4ESMN1; SMN2 | |
| SCHEMBL29941803 | 0.86 | HDAC4 (0.42) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL29941821 | 0.85 | ADRB2 (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222911-A1 | PYRIMIDONE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-27 | — | — | WO | disclosed |
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |