Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893596 | 1.00 | ADRB2 (0.39) | ADRB2GPR52ALDH1A1L3MBTL1HTT | |
| SCHEMBL28889291 | 0.92 | ADRB2 (0.39) | ADRB2ALDH1A1L3MBTL1HTTTDP1 | |
| SCHEMBL29893566 | 0.92 | ADRB2 (0.39) | ADRB2ALDH1A1L3MBTL1HTTTDP1 | |
| SCHEMBL29942367 | 0.91 | ADRB2 (0.40) | ADRB2GPR52ALDH1A1L3MBTL1TACR1 | |
| SCHEMBL28889279 | 0.90 | ADRB2 (0.40) | ADRB2GPR52ALDH1A1L3MBTL1HTT | |
| SCHEMBL29942209 | 0.88 | ADRB2 (0.38) | ADRB2ALDH1A1L3MBTL1PHGDHGAA | |
| SCHEMBL28889299 | 0.87 | HDAC4 (0.40) | ADRB2GPR52ALDH1A1HTTTDP1 | |
| SCHEMBL28889382 | 0.81 | ADRB2 (0.39) | ADRB2ALDH1A1L3MBTL1GAAKCNN4 | |
| SCHEMBL29942075 | 0.81 | ADRB2 (0.42) | ADRB2GPR52ALDH1A1L3MBTL1HTT | |
| SCHEMBL29893632 | 0.80 | ADRB2 (0.37) | ADRB2ALDH1A1L3MBTL1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |