Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640946 | 0.83 | ACACB (0.36) | PRKCZACACBACACAKDM4EKMT2A | |
| SCHEMBL4553606 | 0.82 | ACACB (0.36) | PRKCZACACBACACAKDM4EKMT2A | |
| SCHEMBL158112 | 0.81 | ACACB (0.45) | PRKCZACACBACACAPPARGPARP1 | |
| Hydrochloric Acid SCHEMBL4437775 | 0.78 | ACACB (0.44) | PRKCZACACBACACAPARP1PARP2 | |
| SCHEMBL14855819 | 0.78 | KMT2A (0.35) | PRKCZACACBACACAPARP1KDM4E | |
| SCHEMBL1118704 | 0.77 | ACACB (0.39) | PRKCZACACBACACAPARP1PARP2 | |
| SCHEMBL28048356 | 0.77 | ACACB (0.44) | PRKCZACACBACACAPARP1PARP2 | |
| SCHEMBL8848140 | 0.77 | ACACB (0.44) | PRKCZACACBACACAKDM4EKMT2A | |
| SCHEMBL19342748 | 0.76 | KDM4E (0.44) | PRKCZACACBACACAPARP1KDM4E | |
| SCHEMBL3707018 | 0.75 | ACACB (0.43) | ACACBACACAPPARGKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112251770-B | Novel electrochemical preparation method of antihypertensive drug telmisartan intermediate | 湖南大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-111041516-B | New preparation method of telmisartan intermediate of antihypertensive drug | 湖南大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-112251770-A | Novel electrochemical preparation method of antihypertensive drug telmisartan intermediate | 湖南大学 | 2021-01-22 | — | — | CN | disclosed |
| CN-111041516-A | New preparation method of telmisartan intermediate of antihypertensive drug | 湖南大学 | 2020-04-21 | — | — | CN | disclosed |