Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640946 | 0.90 | ACACB (0.36) | ACACBACACAKMT2AKDM4EALDH1A1 | |
| SCHEMBL19342748 | 0.83 | KDM4E (0.44) | ACACBACACAKMT2AKDM4EALDH1A1 | |
| SCHEMBL14855819 | 0.81 | KMT2A (0.35) | ACACBACACAKMT2AKDM4EALDH1A1 | |
| SCHEMBL1918148 | 0.77 | EGLN1 (0.40) | ACACBACACAKMT2AKDM4EALDH1A1 | |
| SCHEMBL158112 | 0.75 | ACACB (0.45) | ACACBACACAKMT2AKDM4EALDH1A1 | |
| SCHEMBL28048356 | 0.74 | ACACB (0.44) | ACACBACACAKMT2AKDM4EALDH1A1 | |
| SCHEMBL8848140 | 0.74 | ACACB (0.44) | ACACBACACAKMT2AKDM4EPRKCZ | |
| SCHEMBL3712698 | 0.73 | KMT2A (0.38) | ACACBACACAKMT2AKDM4EALDH1A1 | |
| SCHEMBL17801869 | 0.73 | KDM4E (0.38) | ACACBACACAKMT2AKDM4EALDH1A1 | |
| SCHEMBL9754820 | 0.73 | KMT2A (0.37) | ACACBACACAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123483-A1 | PROCESS FOR PREPARATION OF TELMISARTAN | ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) | 2009-10-08 | — | — | WO | disclosed |