Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070384 | 0.83 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHTR1AHTR7 | |
| SCHEMBL6301694 | 0.82 | MAPT (0.72) | MAPTALDH1A1HTR1AHTR7GFER | |
| Hydrochloric Acid SCHEMBL1374296 | 0.81 | MAPT (0.70) | MAPTALDH1A1KDM4EHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL11024728 | 0.81 | MAPT (0.60) | MAPTALDH1A1KDM4EHTR1AHTR7 | |
| SCHEMBL3709528 | 0.79 | MAPT (0.68) | MAPTALDH1A1KDM4EHTR1AHTR7 | |
| SCHEMBL4172010 | 0.79 | MAPT (0.68) | MAPTALDH1A1HTR1AHTR7GFER | |
| SCHEMBL4172008 | 0.79 | MAPT (0.68) | MAPTALDH1A1HTR1AHTR7GFER | |
| SCHEMBL4524807 | 0.78 | MAPT (0.57) | MAPTALDH1A1HTR1AHTR7GFER | |
| SCHEMBL12297794 | 0.78 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EGFERTSHR | |
| SCHEMBL351380 | 0.78 | POLB (0.74) | MAPTALDH1A1KDM4EHTR1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111100079-B | Febrifugine derivatives and preparation method and application thereof | 重庆市畜牧科学院 | 2021-03-19 | — | — | CN | disclosed |
| CN-111100079-A | Febrifugine derivatives and preparation method and application thereof | 重庆市畜牧科学院 | 2020-05-05 | — | — | CN | disclosed |