SCHEMBL288904

SCHEMBL288904

Cc1cccc2scnc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 1/20 0.45
MAPT P10636 2/20 0.36
PARP1 P09874 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
GAA P10253 2/20 0.34
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
PKM P14618 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
BRPF1 P55201 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29967087 1.00 ALDH1A1 (0.46) ALDH1A1HSD17B10MAPTPARP1NPC1
Nitrogen SCHEMBL29241843 0.96 ALDH1A1 (0.43) ALDH1A1HSD17B10MAPTPARP1NPC1
Hydrazine SCHEMBL5242106 0.96 ALDH1A1 (0.47) ALDH1A1HSD17B10MAPTPARP1NPC1
SCHEMBL7170287 0.89 ALDH1A1 (0.39) ALDH1A1HSD17B10MAPTNPC1RAB9A
Aniline SCHEMBL11350739 0.88 ALDH1A1 (0.45) ALDH1A1HSD17B10MAPTPARP1NPC1
SCHEMBL12637458 0.83 ALDH1A1 (0.42) ALDH1A1HSD17B10NPC1RAB9ACYP1A2
SCHEMBL10900782 0.81 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPTPARP1NPC1
SCHEMBL8512104 0.80 TLR8 (0.35) ALDH1A1HSD17B10MAPTNPC1RAB9A
SCHEMBL30586371 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10MAPTPARP1HTR1A
SCHEMBL1823788 0.78 NPC1 (0.33) ALDH1A1NPC1RAB9AGAATRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1055 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024103023-A2 12-LIPOXYGENASE INHIBITORS FOR THE TREATMENT OF LUPUS VERALOX THERAPEUTICS (US) 2024-05-16 WO claimed
WO-2024097846-A1 ORAL PHARMACEUTICAL FORMULATIONS CONTAINING 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES VERALOX THERAPEUTICS (US) 2024-05-10 WO claimed
CN-114891039-B Preparation method of Dufulin compound 广西田园生化股份有限公司 2024-03-29 CN claimed
WO-2024019959-A1 COMPOSITIONS FOR MODULATING LIPOXYGENASE AND METHODS OF USING SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-25 WO claimed
EP-3054936-B1 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS EASTERN VIRGINIA MEDICAL SCHOOL (US) 2023-10-18 EP claimed
CN-109314187-B Solvent blend for photoactive layers 剑桥显示技术有限公司 2023-08-29 CN claimed
CN-110845536-B Acylhydrazone derivative containing phosphonate ester and preparation method and application thereof 淮北师范大学 2023-02-17 CN claimed
CN-115504942-A Synthesis method of alkyl or acyl substituted benzothiazole derivative 汕头大学 2022-12-23 CN claimed
CN-114891039-A Preparation method of Dufulin compound 广西田园生化股份有限公司 2022-08-12 CN claimed
WO-2021176428-A1 PHENANTHROLINE, CARBAZOLE AND FLAVYLIUM BASED CYANINES AND COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2021-09-10 WO claimed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 US claimed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 EP claimed
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-5202221-A Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
CN-1049164-A Suppress Aminooligohydroxy derivatives of feritin and preparation method thereof HOECHST AG (DE) 1991-02-13 CN claimed
EP-0368327-A2 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-05-16 EP claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed