Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1784140 | 0.92 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL27565732 | 0.91 | TSHR (0.47) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL27592318 | 0.91 | TSHR (0.50) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL28052651 | 0.91 | TSHR (0.50) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL27592333 | 0.90 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL28997517 | 0.90 | DAO (0.45) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL27593498 | 0.89 | TSHR (0.48) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL11707346 | 0.86 | TSHR (0.54) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL227466 | 0.86 | TSHR (0.54) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL17595203 | 0.86 | DAO (0.54) | TSHRDAONAPRTSRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111234064-B | Solid catalyst component for olefin polymerization, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2021-08-03 | — | — | CN | disclosed |
| CN-111234064-A | Solid catalyst component for olefin polymerization, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2020-06-05 | — | — | CN | disclosed |