Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11707346 | 1.00 | TSHR (0.54) | TSHRDAONAPRTSRD5A2CES2 | |
| Terephthalic Acid SCHEMBL27698134 | 0.92 | TSHR (0.50) | TSHRDAONAPRTSRD5A2ALDH1A1 | |
| Benzoic Acid SCHEMBL1784140 | 0.90 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL27592318 | 0.89 | TSHR (0.50) | TSHRDAONAPRTSRD5A2CES2 | |
| Isophthalic Acid SCHEMBL11558426 | 0.89 | CA12 (0.46) | ALDH1A1MAPK1SMN1; SMN2RAB9AKMT2A | |
| Benzoic Acid SCHEMBL28052651 | 0.89 | TSHR (0.50) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzophenone SCHEMBL27943881 | 0.89 | ALDH1A1 (0.54) | SRD5A2ALDH1A1MAPK1SMN1; SMN2RAB9A | |
| Benzoic Acid SCHEMBL27592333 | 0.88 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL27593498 | 0.87 | TSHR (0.48) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL28596822 | 0.86 | TSHR (0.56) | TSHRDAONAPRTSRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109795-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2026-04-23 | — | — | US | claimed |
| EP-4598999-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | Eastman Chemical Company (US) | 2025-08-13 | — | — | EP | claimed |
| WO-2024076953-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2024-04-11 | — | — | WO | claimed |
| US-10773501-B2 | Multiple layer interlayer resisting defect formation | SOLUTIA INC. (US) | 2020-09-15 | — | — | US | claimed |
| EP-3200994-B1 | MULTIPLE LAYER INTERLAYER RESISTING DEFECT FORMATION | SOLUTIA INC (US) | 2019-01-30 | — | — | EP | claimed |
| US-20180354245-A1 | MULTIPLE LAYER INTERLAYER RESISTING DEFECT FORMATION | SOLUTIA INC. (US) | 2018-12-13 | — | — | US | claimed |
| US-10065399-B2 | Polymer interlayers comprising a blend of two or more resins | SOLUTIA INC. (US) | 2018-09-04 | — | — | US | claimed |
| US-9962910-B2 | High flow polymer interlayers for laminated glass | SOLUTIA INC. (US) | 2018-05-08 | — | — | US | claimed |
| US-9914286-B2 | Polymer interlayers having improved optical properties | SOLUTIA INC. (US) | 2018-03-13 | — | — | US | claimed |
| US-20170232719-A1 | POLYMER INTERLAYERS COMPRISING A BLEND OF TWO OR MORE RESINS | SOLUTIA INC. (US) | 2017-08-17 | — | — | US | claimed |
| US-20160101605-A1 | POLYMER INTERLAYERS HAVING IMPROVED OPTICAL PROPERTIES | SOLUTIA INC. (US) | 2016-04-14 | — | — | US | claimed |
| US-20160096350-A1 | MULTIPLE LAYER INTERLAYER RESISTING DEFECT FORMATION | SOLUTIA INC. (US) | 2016-04-07 | — | — | US | claimed |
| US-20160059521-A1 | HIGH FLOW POLYMER INTERLAYERS FOR LAMINATED GLASS | SOLUTIA INC. (US) | 2016-03-03 | — | — | US | claimed |
| CN-105358321-A | Polymer interlayers comprising blends of two or more resins | SOLUTIA INC | 2016-02-24 | — | — | CN | claimed |
| US-9254625-B2 | Polymer interlayers having improved optical properties | SOLUTIA INC. (US) | 2016-02-09 | — | — | US | claimed |
| US-9248626-B2 | Polymer interlayers comprising a blend of two or more resins | SOLUTIA INC. (US) | 2016-02-02 | — | — | US | claimed |
| CN-105283314-A | Polymer interlayers having improved optical properties | SOLUTIA INC | 2016-01-27 | — | — | CN | claimed |
| US-20140364549-A1 | POLYMER INTERLAYERS HAVING IMPROVED OPTICAL PROPERTIES | SOLUTIA INC. (US) | 2014-12-11 | — | — | US | claimed |
| US-20140364550-A1 | POLYMER INTERLAYERS COMPRISING A BLEND OF TWO OR MORE RESINS | SOLUTIA INC. (US) | 2014-12-11 | — | — | US | claimed |
| US-20140363651-A1 | POLYMER INTERLAYERS HAVING IMPROVED OPTICAL PROPERTIES | SOLUTIA INC. (US) | 2014-12-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109795-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | TRIM4, TRIM58, TRA2B | TSHR 3046/4885DAO 3021/4885NAPRT 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.