Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28737041 | 0.85 | NOD1 (0.62) | NOD1NOD2PPARGPPARAALOX5 | |
| SCHEMBL7116279 | 0.84 | NOD1 (0.57) | NOD1NOD2PPARGPPARAALOX5 | |
| SCHEMBL28073898 | 0.84 | NOD1 (0.57) | NOD1NOD2PPARGPPARAALOX5 | |
| SCHEMBL30647189 | 0.84 | NOD1 (0.57) | NOD1NOD2PPARGPPARAALOX5 | |
| SCHEMBL28088463 | 0.84 | NOD1 (0.57) | NOD1NOD2PPARGPPARAALOX5 | |
| SCHEMBL6894989 | 0.84 | NOD1 (0.60) | NOD1NOD2PPARGPPARAALOX5 | |
| SCHEMBL29895778 | 0.84 | PDE4A (0.45) | NOD1NOD2PPARGPPARAALDH3A1 | |
| SCHEMBL6867245 | 0.83 | CA12 (0.54) | NOD1NOD2PPARGPPARAPPARD | |
| SCHEMBL8829929 | 0.82 | NOD1 (0.58) | NOD1NOD2PPARGPPARAALOX5 | |
| SCHEMBL1672682 | 0.81 | NOD1 (0.54) | NOD1NOD2PPARGPPARAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285792-B | 2-substituted indole compound and preparation method thereof | 三峡大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-111285792-A | 2-substituted indole compound and preparation method thereof | 三峡大学 | 2020-06-16 | — | — | CN | disclosed |