Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891179 | 0.93 | DHODH (0.55) | DHODHMEN1KMT2AEIF4A1PDE10A | |
| SCHEMBL28891171 | 0.92 | DHODH (0.58) | DHODHMEN1KMT2AEIF4A1PDE10A | |
| SCHEMBL28891208 | 0.92 | DHODH (0.60) | DHODHMEN1KMT2APDE10APLA2G2A | |
| SCHEMBL28885855 | 0.90 | DHODH (0.65) | DHODHMEN1KMT2AEIF4A1PDE10A | |
| SCHEMBL28885856 | 0.88 | DHODH (0.61) | DHODHMEN1KMT2AEIF4A1PDE10A | |
| SCHEMBL28891175 | 0.86 | DHODH (0.55) | DHODHMEN1KMT2AEIF4A1PDE10A | |
| SCHEMBL23579598 | 0.86 | DHODH (0.66) | DHODHMEN1KMT2AEIF4A1PDE10A | |
| SCHEMBL29996591 | 0.86 | DHODH (0.66) | DHODHMEN1KMT2AEIF4A1PDE10A | |
| SCHEMBL28891192 | 0.85 | DHODH (0.53) | DHODHMEN1KMT2AEIF4A1PDE10A | |
| SCHEMBL28891182 | 0.85 | DHODH (0.53) | DHODHMEN1KMT2AEIF4A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115361948-A | Methods and compositions for inhibiting dihydroorotate dehydrogenase | 俄亥俄州国家创新基金会 | 2022-11-18 | — | — | CN | disclosed |