Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 2/20 | 0.30 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17543819 | 0.99 | TRPV4 (0.36) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17542718 | 0.92 | TRPV4 (0.38) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17543057 | 0.91 | TRPV4 (0.39) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17543733 | 0.90 | TRPV4 (0.37) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17544054 | 0.90 | TRPV4 (0.37) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17543786 | 0.89 | TRPV4 (0.38) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17543156 | 0.88 | TRPV4 (0.39) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17543977 | 0.88 | TRPV4 (0.36) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17542898 | 0.88 | TRPV4 (0.38) | TRPV4GRM5TRPM8DDB1CRBN | |
| SCHEMBL17544103 | 0.88 | TRPV4 (0.40) | TRPV4GRM5TRPM8DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795117-B | Heterobicyclic compounds and their use for the treatment of tuberculosis | 大塚制药株式会社 | 2020-06-26 | — | — | CN | disclosed |