Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577103 | 0.90 | THRB (0.53) | THRBTHRAMEN1KMT2ANPSR1 | |
| SCHEMBL1058506 | 0.90 | THRB (0.53) | THRBTHRAMEN1KMT2ANPSR1 | |
| SCHEMBL14173222 | 0.89 | THRB (0.51) | THRBTHRAMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19749006 | 0.88 | THRB (0.51) | THRBTHRAMEN1KMT2ANPSR1 | |
| SCHEMBL29413361 | 0.84 | THRB (0.56) | THRBTHRAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3841280 | 0.84 | THRB (0.56) | THRBTHRAMEN1KMT2ASMN1; SMN2 | |
| Acrylic Acid Methyl Ester SCHEMBL27885616 | 0.83 | THRB (0.48) | THRBTHRAMEN1KMT2ASMN1; SMN2 | |
| Methacrylic Acid SCHEMBL27688921 | 0.81 | THRB (0.46) | THRBTHRATSHRSMN1; SMN2NPSR1 | |
| Styrene SCHEMBL28776566 | 0.81 | THRB (0.46) | THRBTHRATSHRKDM4EMAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL27715220 | 0.81 | THRB (0.52) | THRBTHRAMEN1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914241-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-110914241-A | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2020-03-24 | — | — | CN | disclosed |