SCHEMBL28892089

SCHEMBL28892089

CCCO[C@@](CCC)(C(=O)O)C(O)C(O)C(O)COP(=O)(O)O

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.41
PGK1 P00558 1/20 0.40
PGK2 P07205 1/20 0.40
LPAR5 Q9H1C0 1/20 0.38
S1PR2 O95136 2/20 0.35
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 2/20 0.35
MPI P34949 1/20 0.35
S1PR5 Q9H228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29204294 0.88 LPAR5 (0.39) PGDPGK1PGK2LPAR5S1PR2
SCHEMBL29204260 0.86 LPAR5 (0.44) PGDLPAR5S1PR2S1PR1S1PR3
SCHEMBL29204300 0.85 LPAR5 (0.46) LPAR5S1PR2S1PR1S1PR3S1PR5
SCHEMBL28892055 0.85 LPAR5 (0.46) LPAR5S1PR2S1PR1S1PR3S1PR5
SCHEMBL28892066 0.81 PGD (0.45) PGDPGK1PGK2LPAR5S1PR2
SCHEMBL25393911 0.76 CYP2C9 (0.31) PGD
SCHEMBL18007397 0.76 CYP2C9 (0.31) PGD
SCHEMBL28892063 0.75 PGD (0.42) PGDPGK1PGK2MPI
SCHEMBL28892075 0.75 PGD (0.39) PGDPGK1PGK2LPAR5S1PR2
SCHEMBL28892048 0.70 PGD (0.47) PGDPGK1PGK2S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115364110-B Application of 6-phosphogluconic acid and derivatives thereof in preparation of medicines for preventing or treating sugar metabolic disorder diseases 复旦大学 2024-05-07 CN disclosed
CN-115364110-A Application of 6-phosphogluconic acid and derivatives thereof in preparing medicines for preventing or treating glycometabolism disorder diseases 复旦大学 2022-11-22 CN disclosed