Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735359 | 0.88 | MAPT (0.49) | MAPTKDM4EPOLBATMABL1 | |
| SCHEMBL30402103 | 0.88 | MAPT (0.49) | MAPTKDM4EPOLBATMABL1 | |
| SCHEMBL522791 | 0.77 | MAPT (0.63) | MAPTKDM4EPOLBATMMAPK8 | |
| SCHEMBL29580762 | 0.77 | MAPT (0.63) | MAPTKDM4EPOLBATMMAPK8 | |
| SCHEMBL1011953 | 0.75 | MAPT (0.54) | MAPTKDM4EPOLBATMABL1 | |
| SCHEMBL11055936 | 0.75 | MAPT (0.61) | MAPTKDM4EPOLBATMMAPK8 | |
| SCHEMBL28866217 | 0.75 | MAPT (0.61) | MAPTKDM4EPOLBATMMAPK8 | |
| SCHEMBL28775345 | 0.75 | MAPT (0.61) | MAPTKDM4EPOLBATMMAPK8 | |
| SCHEMBL24704091 | 0.74 | MAPT (0.43) | MAPTKDM4EPOLBATMABL1 | |
| SCHEMBL30104315 | 0.74 | MAPT (0.43) | MAPTKDM4EPOLBATMABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |