SCHEMBL522791

SCHEMBL522791

COC(=O)c1cccc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.63
PLK1 P53350 1/20 0.61
ALDH1A1 P00352 4/20 0.60
KDM4E B2RXH2 4/20 0.60
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
ALOX12 P18054 1/20 0.60
NR4A2 P43354 2/20 0.59
NR4A1 P22736 1/20 0.59
NR4A3 Q92570 1/20 0.59
MMP3 P08254 1/20 0.58
HDAC8 Q9BY41 1/20 0.58
MAPK8 P45983 1/20 0.57
MAPK9 P45984 1/20 0.57
MAPK10 P53779 1/20 0.57
POLB P06746 2/20 0.57
GAA P10253 1/20 0.57
LMNA P02545 1/20 0.57
TSHR P16473 1/20 0.57
HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580762 1.00 MAPT (0.63) MAPTPLK1ALDH1A1KDM4EKMT2A
SCHEMBL28866217 0.98 MAPT (0.61) MAPTPLK1ALDH1A1KDM4EKMT2A
SCHEMBL28775345 0.98 MAPT (0.61) MAPTPLK1ALDH1A1KDM4EKMT2A
SCHEMBL11055936 0.98 MAPT (0.61) MAPTPLK1ALDH1A1KDM4EKMT2A
SCHEMBL9485623 0.89 MAPT (0.54) MAPTPLK1ALDH1A1KDM4EKMT2A
Naphthoic Acid SCHEMBL17143551 0.88 NR4A1 (0.70) MAPTPLK1ALDH1A1KDM4EKMT2A
SCHEMBL70429 0.87 LMNA (0.59) MAPTALDH1A1KDM4EKMT2AMEN1
SCHEMBL10010690 0.85 SLC6A3 (0.58) MAPTPLK1ALDH1A1KDM4EKMT2A
SCHEMBL12486711 0.85 MAPT (0.54) MAPTPLK1ALDH1A1KDM4EKMT2A
SCHEMBL27673982 0.85 PLK1 (0.54) MAPTPLK1ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 516 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115612095-B High-temperature-resistant semi-aromatic copolyamide, preparation method thereof, composition and molded product 上海凯赛生物技术股份有限公司 2024-11-26 CN claimed
CN-118183669-A Preparation method of lithium iron phosphate by substituting aromatic compound for linear carbon source 四川万鹏时代科技股份有限公司 2024-06-14 CN claimed
CN-113817158-B Preparation method of high-temperature-resistant nylon resin 浙江新力新材料股份有限公司 2022-04-29 CN claimed
CN-111995746-B Bio-based high-temperature-resistant polyamide composite material, low-temperature pre-polycondensation preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-01-28 CN claimed
CN-111961199-B Bio-based high-temperature-resistant polyamide composite material, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-01-28 CN claimed
CN-113817158-A Preparation method of high-temperature-resistant nylon resin 浙江新力新材料股份有限公司 2021-12-21 CN claimed
CN-110467724-A A kind of preparation method of semi-aromatic nylon ZHEJIANG SHINY NEW MAT CO LTD 2019-11-19 CN claimed
CN-109575277-A A kind of preparation method of high-fire resistance nylon 浙江新力新材料股份有限公司 2019-04-05 CN claimed
CN-109071506-A Substituted 2- (miscellaneous) Aryimidazole yl-carboxamides as pest control agent 拜耳作物科学股份公司 2018-12-21 CN claimed
CN-106050480-B The vehicle-mounted hydrogen-feeding system of liquid organic hydride suitable for hydrogen energy automobile 浙江大学 2018-09-14 CN claimed
CN-1741784-A Functional Fragrance Precursors COLGATE PALMOLIVE CO (US) 2006-03-01 CN claimed
CN-1738650-A Improved gastrin releasing peptide compounds BRACCO IMAGING SPA (IT) 2006-02-22 CN claimed
EP-1615890-A1 PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION WARNER-LAMBERT COMPANY (US) 2006-01-18 EP claimed
US-20050227168-A1 UV radiation blocking protective layers compatible with thick film pastes E. I. DU PONT DE NEMOURS AND COMPANY 2005-10-13 US claimed
WO-2005077032-A2 UV RADIATION BLOCKING PROTECTIVE LAYERS COMPATIBLE WITH THICK FILM PASTES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-08-25 WO claimed
WO-2004089903-A1 PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION WARNER-LAMBERT COMPANY LLC (US) 2004-10-21 WO claimed
CN-1365665-A Synergistic composition containing ascorbate and lysine for diseases related to extracellular matrix degradation LATE MATIAS (NL) 2002-08-28 CN claimed
CN-1072930-C Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug MCNEILAB INC (US) 2001-10-17 CN claimed
CN-1185103-A Homogeneous water-in-perfluorochemical stable liquid dispersion for pulmonary administration to animals HEMAGEN PFC (US) 1998-06-17 CN claimed
CN-1073095-A The compositions that contains a kind of tramadol composition and a kind of nonsteroidal anti-inflammatory drug MCNEILAB INC (US) 1993-06-16 CN claimed