Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11730776 | 0.98 | GAA (0.46) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL7621228 | 0.93 | SMN1; SMN2 (0.44) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL862004 | 0.88 | LTA4H (0.43) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL8518114 | 0.88 | GAA (0.53) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL8824199 | 0.85 | TSHR (0.36) | GAASMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL7774719 | 0.82 | TSHR (0.50) | GAAALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1632530 | 0.82 | GAA (0.50) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL713525 | 0.81 | — | — | |
| SCHEMBL1439008 | 0.81 | MGAM (0.45) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL14639176 | 0.81 | GAA (0.45) | GAAMGAMSIMGAM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101525303-A | Novel 9- substituted minocycline compounds | TUFTS UNIVERSITY TRUSTEE (US) | 2009-09-09 | — | — | CN | claimed |
| CN-1690047-A | 9-substituted minocycline compounds | TUFTS COLLEGE (US) | 2005-11-02 | — | — | CN | claimed |
| CN-1471509-A | 9-substituted minocycline compounds | ���Ĵ���ѧ | 2004-01-28 | — | — | CN | claimed |
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | claimed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | claimed |
| CN-85108347-A | Plant growth regulator | — | 1986-06-10 | — | — | CN | claimed |
| EP-0181494-A1 | Plant growth regulation agent | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-05-21 | — | — | EP | claimed |
| JP-61091105-A | — | — | None | — | — | JP | disclosed |
| JP-61091106-A | — | — | None | — | — | JP | disclosed |
| JP-61091104-A | — | — | None | — | — | JP | disclosed |
| US-20220071971-A1 | MACROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2022-03-10 | — | — | US | disclosed |
| EP-3898621-A1 | MACROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | Novartis AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-113227087-A | Macrocyclic compounds and their use in the treatment of disease | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| JP-S6191106-A | PLANT GROWTH REGULATOR FOR POTATOES | MITSUBISHI GAS CHEM CO INC | 1986-05-09 | — | — | JP | disclosed |
| JP-S6191104-A | PLANT GROWTH REGULATOR FOR BEANS | MITSUBISHI GAS CHEM CO INC | 1986-05-09 | — | — | JP | disclosed |
| JP-S6191105-A | PLANT GROWTH REGULATOR FOR WHEAT (BARLEY) | MITSUBISHI GAS CHEM CO INC | 1986-05-09 | — | — | JP | disclosed |
| EP-0178759-A1 | Alkynyl derivativesof pyrazolo-(3,4-b)-pyridine lactams | ICI AMERICAS INC. (US) | 1986-04-23 | — | — | EP | disclosed |
| US-4562202-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |
| US-4086094-A | HYDROPHILIC COLLOID LAYER | FUJI PHOTO FILM CO., LTD. (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4005208-A | GASTRIC JUICE, ANTISECRETORY | SMITHKLINE CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220071971-A1 | MACROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE | CFTR, PKD1, PKD2 | GAA 71/4885MGAM 1572/4885SI 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.