Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28959994 | 0.86 | HPGD (0.45) | L3MBTL1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL30668196 | 0.85 | HTR1B (0.46) | L3MBTL1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL28960000 | 0.85 | HTR1B (0.46) | L3MBTL1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL30394059 | 0.85 | CD274 (0.39) | L3MBTL1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL19897916 | 0.85 | CD274 (0.39) | L3MBTL1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL10681054 | 0.81 | HTR1B (0.45) | L3MBTL1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL10677209 | 0.80 | TP53 (0.49) | L3MBTL1TSHRRAB9AALDH1A1TDP1 | |
| SCHEMBL11020759 | 0.80 | ALDH1A1 (0.45) | L3MBTL1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL3433833 | 0.79 | CYP2D6 (0.56) | L3MBTL1HPGDTSHRRAB9ANPC1 | |
| SCHEMBL11097966 | 0.78 | CYP1A2 (0.47) | L3MBTL1TSHRRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368090-B | Compounds as immunomodulators | 百时美施贵宝公司 | 2022-04-12 | — | — | CN | disclosed |