Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.64 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.64 |
| ▸ | KDR | P35968 | 5/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 2/20 | 0.48 |
| ▸ | TEK | Q02763 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421211 | 0.83 | SRC (0.66) | SRCTGFBR1KDRPDGFRAMET | |
| SCHEMBL3901030 | 0.81 | SRC (0.76) | SRCTGFBR1KDRPDGFRAAURKA | |
| SCHEMBL3895885 | 0.81 | SRC (0.80) | SRCTGFBR1KDRPDGFRAFGFR2 | |
| SCHEMBL3896025 | 0.81 | SRC (0.69) | SRCTGFBR1KDRPDGFRAAURKA | |
| SCHEMBL3893930 | 0.81 | SRC (0.69) | SRCTGFBR1KDRPDGFRAAURKA | |
| SCHEMBL3895528 | 0.80 | SRC (0.67) | SRCTGFBR1KDRPDGFRAAURKA | |
| SCHEMBL10296329 | 0.79 | PDGFRB (0.55) | SRCTGFBR1PDGFRAFGFR2 | |
| SCHEMBL3906557 | 0.79 | SRC (0.60) | SRCTGFBR1KDRPDGFRAFGFR2 | |
| SCHEMBL28426786 | 0.79 | SRC (0.57) | SRCTGFBR1KDRPDGFRAAURKA | |
| SCHEMBL3906484 | 0.78 | SRC (0.86) | SRCTGFBR1KDRPDGFRAFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |
| CN-111253385-A | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2020-06-09 | — | — | CN | disclosed |