Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.57 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 8/20 | 0.48 |
| ▸ | AURKA | O14965 | 5/20 | 0.48 |
| ▸ | LCK | P06239 | 5/20 | 0.48 |
| ▸ | MET | P08581 | 5/20 | 0.48 |
| ▸ | TEK | Q02763 | 5/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | FGR | P09769 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430853 | 0.86 | SRC (0.55) | SRCTGFBR1KRASSOS1KDR | |
| Hydrochloric Acid SCHEMBL23359655 | 0.80 | KRAS (0.55) | TGFBR1KRASSOS1PDGFRAKIT | |
| SCHEMBL28430848 | 0.79 | KDR (0.52) | SRCKDRAURKALCKMET | |
| SCHEMBL28893844 | 0.79 | SRC (0.64) | SRCTGFBR1KDRAURKALCK | |
| SCHEMBL28421211 | 0.78 | SRC (0.66) | SRCTGFBR1KDRMETPDGFRA | |
| SCHEMBL16296005 | 0.77 | DDB1 (0.55) | — | |
| SCHEMBL3895885 | 0.76 | SRC (0.80) | SRCTGFBR1KDRAURKALCK | |
| SCHEMBL3901030 | 0.76 | SRC (0.76) | SRCTGFBR1KDRAURKALCK | |
| Hydrochloric Acid SCHEMBL16296004 | 0.76 | DDB1 (0.54) | — | |
| SCHEMBL3896025 | 0.76 | SRC (0.69) | SRCTGFBR1KDRAURKALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |
| CN-111253385-A | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2020-06-09 | — | — | CN | disclosed |