SCHEMBL28894113

SCHEMBL28894113

COc1cccc2c1ccn2-c1ccccc1I

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.47
HTR2C P28335 1/20 0.44
FABP4 P15090 2/20 0.40
FFAR4 Q5NUL3 1/20 0.40
HTR7 P34969 2/20 0.39
HTR1A P08908 1/20 0.39
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
RHEB Q15382 1/20 0.38
GAA P10253 1/20 0.38
PRMT5 O14744 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
MGLL Q99685 1/20 0.36
GRM1 Q13255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712008 0.83 HTR2C (0.47) HTR6HTR2CFABP4FFAR4HTR7
SCHEMBL28894100 0.79 HTR2A (0.41) HTR2CFABP4HTR7PRMT5MGLL
SCHEMBL3419581 0.78 FFAR4 (0.46) HTR6HTR2CFABP4FFAR4BCHE
SCHEMBL31460349 0.77 MEN1 (0.41) HTR2CFABP4BCHEACHEGAA
SCHEMBL29152806 0.77 GAA (0.43) HTR6HTR2CHTR7HTR1AGAA
SCHEMBL28894097 0.76 HTR2A (0.40) HTR6HTR2CFABP4RHEBPRMT5
SCHEMBL28893985 0.76 NOTUM (0.42) HTR6MGLL
SCHEMBL28894095 0.76 HSP90AA1 (0.44) MGLL
SCHEMBL13209348 0.73 HTR2C (0.49) HTR6HTR2CFABP4FFAR4RHEB
SCHEMBL23883999 0.73 FFAR4 (0.52) HTR6HTR2CFFAR4RHEBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371451-A Method for efficiently synthesizing silicon-based indole compound 南阳师范学院 2025-01-28 CN claimed
CN-115043847-B Preparation method of 10H-indolo [1,2-a ] indol-10-one compound 西北师范大学 2023-05-26 CN claimed
CN-115043847-A Preparation method of 10H-indolo [1,2-a ] indol-10-one compound 西北师范大学 2022-09-13 CN claimed
CN-119371451-A Method for efficiently synthesizing silicon-based indole compound 南阳师范学院 2025-01-28 CN disclosed
CN-115043847-B Preparation method of 10H-indolo [1,2-a ] indol-10-one compound 西北师范大学 2023-05-26 CN disclosed
CN-115043847-A Preparation method of 10H-indolo [1,2-a ] indol-10-one compound 西北师范大学 2022-09-13 CN disclosed