Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894027 | 0.84 | KDM4E (0.40) | ALKBH5FTOKDM4ENQO2MGLL | |
| SCHEMBL31454929 | 0.81 | HTR2A (0.43) | HTR2AHTR2CALKBH5FTOFABP4 | |
| SCHEMBL28894095 | 0.79 | HSP90AA1 (0.44) | MGLL | |
| SCHEMBL28894097 | 0.79 | HTR2A (0.40) | HTR2AHTR2CFABP4MGLLP2RX7 | |
| SCHEMBL28893985 | 0.79 | NOTUM (0.42) | ALDH1A1CYP2A6CYP1A2MGLL | |
| SCHEMBL28894113 | 0.79 | HTR6 (0.47) | HTR2CFABP4MGLLHTR7PRMT5 | |
| SCHEMBL29600322 | 0.78 | HTR2A (0.37) | HTR2AHTR2CALKBH5FTOFABP4 | |
| SCHEMBL9428481 | 0.78 | TSHR (0.46) | HTR2AHTR2CALKBH5FTOALDH1A1 | |
| SCHEMBL25662730 | 0.77 | HTR2A (0.44) | HTR2AHTR2CALKBH5FTOFABP4 | |
| SCHEMBL9429365 | 0.76 | FABP4 (0.56) | FABP4ALDH1A1KDM4EHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371451-A | Method for efficiently synthesizing silicon-based indole compound | 南阳师范学院 | 2025-01-28 | — | — | CN | claimed |
| CN-115043847-B | Preparation method of 10H-indolo [1,2-a ] indol-10-one compound | 西北师范大学 | 2023-05-26 | — | — | CN | claimed |
| CN-115043847-A | Preparation method of 10H-indolo [1,2-a ] indol-10-one compound | 西北师范大学 | 2022-09-13 | — | — | CN | claimed |
| CN-119371451-A | Method for efficiently synthesizing silicon-based indole compound | 南阳师范学院 | 2025-01-28 | — | — | CN | disclosed |
| CN-115043847-B | Preparation method of 10H-indolo [1,2-a ] indol-10-one compound | 西北师范大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-115043847-A | Preparation method of 10H-indolo [1,2-a ] indol-10-one compound | 西北师范大学 | 2022-09-13 | — | — | CN | disclosed |