Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPIN4 | Q56A73 | 1/20 | 0.55 |
| ▸ | SPIN3 | Q5JUX0 | 1/20 | 0.55 |
| ▸ | SPIN2B | Q9BPZ2 | 1/20 | 0.55 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.55 |
| ▸ | WHR1 | P49842 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 11/20 | 0.52 |
| ▸ | RCOR1 | Q9UKL0 | 11/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 9/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894334 | 0.85 | SPIN4 (0.53) | SPIN4SPIN3SPIN2BSPIN1WHR1 | |
| SCHEMBL28894176 | 0.81 | TLR9 (0.64) | TLR7ENPP1TLR9 | |
| SCHEMBL28894133 | 0.79 | SMN1; SMN2 (0.65) | EHMT2ENPP1 | |
| SCHEMBL28894141 | 0.77 | ENPP1 (0.51) | SPIN4SPIN3SPIN2BSPIN1TLR7 | |
| SCHEMBL10910816 | 0.75 | ENPP1 (0.78) | ENPP1 | |
| SCHEMBL30081011 | 0.75 | ENPP1 (0.53) | WHR1KDM1AENPP1 | |
| SCHEMBL28959656 | 0.75 | ENPP1 (0.53) | WHR1KDM1AENPP1 | |
| SCHEMBL22407601 | 0.73 | ENPP1 (0.75) | ENPP1 | |
| SCHEMBL20771328 | 0.73 | ENPP1 (0.52) | TLR7ENPP1 | |
| SCHEMBL28894177 | 0.73 | ENPP1 (0.52) | WHR1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362150-A | ENPP1 inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2022-11-18 | — | — | CN | disclosed |