Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.63 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.63 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.63 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.63 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.63 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.63 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.63 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23231215 | 0.93 | GPBAR1 (0.72) | GPBAR1LMNAMEN1KMT2AAKR1B10 | |
| SCHEMBL288122 | 0.93 | GPBAR1 (0.72) | GPBAR1LMNAMEN1KMT2AAKR1B10 | |
| SCHEMBL288704 | 0.93 | GPBAR1 (0.72) | GPBAR1LMNAMEN1KMT2AAKR1B10 | |
| SCHEMBL2467588 | 0.92 | GPBAR1 (0.72) | GPBAR1LMNAMEN1KMT2AAKR1B10 | |
| SCHEMBL7532429 | 0.92 | GPBAR1 (0.68) | GPBAR1LMNAMEN1KMT2AAKR1B10 | |
| Cholic Acid SCHEMBL437269 | 0.90 | GPBAR1 (0.71) | GPBAR1LMNAMEN1KMT2AAKR1B10 | |
| Cholic Acid SCHEMBL288946 | 0.90 | GPBAR1 (0.78) | GPBAR1LMNAMEN1KMT2AAKR1B10 | |
| Cholic Acid SCHEMBL437268 | 0.90 | GPBAR1 (0.78) | GPBAR1LMNAMEN1KMT2AAKR1B10 | |
| SCHEMBL1758946 | 0.88 | GPBAR1 (0.67) | GPBAR1LMNAMEN1KMT2ATDP1 | |
| SCHEMBL1287858 | 0.88 | GPBAR1 (0.78) | GPBAR1LMNAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2449488-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES Life Sciences AG (AT) | 2012-05-09 | — | — | EP | disclosed |
| EP-2427773-A1 | METHOD OF DIAGNOSING ASPHYXIA | Keller, Matthias (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2011000753-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES LIFE SCIENCES AG (AT) | 2011-01-06 | — | — | WO | disclosed |
| WO-2010128054-A1 | METHOD OF DIAGNOSING ASPHYXIA | BIOCRATES LIFE SCIENCES AG (AT) | 2010-11-11 | — | — | WO | disclosed |
| WO-1996038464-A1 | ANTIMICROBIAL STEROL CONJUGATES | LEHIGH UNIVERSITY (US) | 1996-12-05 | — | — | WO | disclosed |