Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501371 | 0.82 | MAPT (0.50) | MAPTPTGDR2KMT2ATHRBHTT | |
| SCHEMBL17784859 | 0.80 | MAPT (0.47) | MAPTPTGDR2KMT2ABRD4BRD2 | |
| SCHEMBL19513362 | 0.80 | MAPT (0.53) | MAPTPTGDR2KMT2ATHRBHTT | |
| SCHEMBL17784762 | 0.78 | MAPT (0.45) | MAPTPTGDR2KMT2ABRD4BRD2 | |
| SCHEMBL22491805 | 0.76 | MAPT (0.44) | MAPTPTGDR2KMT2ABRD4BRD2 | |
| SCHEMBL22148816 | 0.76 | HTT (0.39) | MAPTPTGDR2THRBHTT | |
| SCHEMBL19939512 | 0.76 | BRD4 (0.53) | MAPTPTGDR2BRD4BRD2BRD3 | |
| SCHEMBL19513477 | 0.76 | MAPT (0.41) | MAPTPTGDR2KMT2ABRD4BRD2 | |
| SCHEMBL23347630 | 0.75 | TRPA1 (0.61) | HTTTRPA1POLB | |
| SCHEMBL14520625 | 0.75 | TRPA1 (0.61) | HTTTRPA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111433197-A | Solid forms of plasma kallikrein inhibitors and salts thereof | 卡尔维斯塔制药有限公司 | 2020-07-17 | — | — | CN | disclosed |