Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | APAF1 | O14727 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051200 | 1.00 | KDM4E (0.62) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL28896629 | 0.88 | KDM4E (0.58) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL30052570 | 0.88 | KDM4E (0.58) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL1706855 | 0.82 | PON1 (0.72) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28477622 | 0.76 | ACHE (0.58) | KDM4EKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL29558409 | 0.76 | ACHE (0.58) | KDM4EKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL5940889 | 0.75 | KMT2A (0.69) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL5940948 | 0.74 | KMT2A (0.68) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL6481314 | 0.74 | NPC1 (0.61) | KDM4EKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL28435430 | 0.73 | KDM4E (0.45) | KDM4EKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072619-B | Compound with drug-resistant bacterium resisting effect and preparation method and application thereof | 云南中烟工业有限责任公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-111072619-A | Compound with drug-resistant bacterium resisting effect and preparation method and application thereof | 云南中烟工业有限责任公司 | 2020-04-28 | — | — | CN | disclosed |