SCHEMBL2889557

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2889735	0.90	ROCK2 (0.61)	ROCK2MAPTPOLA1POLBGAA
	SCHEMBL2881832	0.88	ROCK2 (0.69)	ROCK2MAPTPOLA1POLBGAA
	SCHEMBL4406963	0.87	ROCK2 (0.65)	ROCK2MAPTPOLA1POLBGAA
	SCHEMBL2888351	0.78	ROCK2 (0.67)	ROCK2MAPTPOLA1POLBGAA
	SCHEMBL2877122	0.78	ROCK2 (1.00)	ROCK2CYP3A4AXLCDC7DAPK3
	SCHEMBL858840	0.78	TTBK1 (0.59)	MAPTGAAKMT2AAXLROCK1
	SCHEMBL2881534	0.78	TTBK1 (0.54)	AXLROCK1AURKAAURKBTNNI3K
	SCHEMBL2881172	0.76	ROCK2 (0.80)	ROCK2CYP3A4AXLCDC7DAPK3
	SCHEMBL2887470	0.76	ROCK2 (0.65)	ROCK2MAPTPOLA1POLBGAA
	SCHEMBL4416215	0.76	ROCK2 (0.65)	ROCK2MAPTPOLA1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.