Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.66 |
| ▸ | RAB9A | P51151 | 11/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30020507 | 1.00 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL5608972 | 0.92 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL30605183 | 0.85 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL13972841 | 0.84 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL18997841 | 0.81 | GAA (0.54) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL1374759 | 0.80 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL2518498 | 0.80 | LMNA (0.63) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL28895733 | 0.80 | MEN1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL30021380 | 0.80 | MEN1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL3980949 | 0.80 | HDAC6 (0.58) | NPC1RAB9ASMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879810-B | Imidazole ring substituted aminophenol oxygen radical zinc complex and preparation method and application thereof | 华东理工大学 | 2022-10-28 | — | — | CN | disclosed |