Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30028927 | 1.00 | KDM4E (0.32) | KDM4EMAPTMDM2TSHRSMN1; SMN2 | |
| SCHEMBL30029534 | 0.88 | MDM2 (0.32) | KDM4EMAPTMDM2TSHRSMN1; SMN2 | |
| SCHEMBL28896655 | 0.88 | MDM2 (0.32) | KDM4EMAPTMDM2TSHRSMN1; SMN2 | |
| SCHEMBL28896455 | 0.84 | MDM2 (0.33) | MDM2TSHRSMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL28896653 | 0.84 | MDM2 (0.33) | MDM2TSHRSMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL30028600 | 0.80 | CCNT1 (0.37) | KDM4EMAPTTSHRSMN1; SMN2CYP4F2 | |
| SCHEMBL28896305 | 0.80 | CCNT1 (0.37) | KDM4EMAPTTSHRSMN1; SMN2CYP4F2 | |
| SCHEMBL28896633 | 0.69 | MAPT (0.35) | KDM4EMAPTTSHRSMN1; SMN2CYP4F2 | |
| SCHEMBL30028839 | 0.69 | MAPT (0.35) | KDM4EMAPTTSHRSMN1; SMN2CYP4F2 | |
| SCHEMBL28896596 | 0.67 | TSHR (0.36) | MAPTTSHRSMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |